If you feel emails are saturated in the Plesk Qmail mail queue, there is a possibility that your Plesk server is been used for sending spam emails.
On a Plesk server relaying is not allowed by default so following are the ways spamming is mostly done. They are explained below point wise.
1) Using CGI by a user
2) PHP scripts. Also refer the article to locate the directories of the PHP scripts that are sending emails.
3) By a compromised email account
First, lets look at the the mail queue
# /var/qmail/bin/qmail-qstat
messages in [...]
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